New York Blood Center

  • Research Assistant II- Molecular Parasitology

    Job Locations US-NY-New York
    Job ID
    2018-1864
    Category
    Research
    Type
    Regular Full-Time
  • Overview

    At New York Blood Center, one of the most comprehensive blood centers in the world, our focus is on cultivating excellence by merging cutting-edge innovation with diligent customer service, groundbreaking research, and comprehensive program and service development. Join us as we work towards meeting and exceeding the growing needs of our diverse communities, further our lifesaving strategic goals in a rapidly changing environment, and expand our impact on the local, national, and global communities we serve.

    Responsibilities

    As a key member of our Molecular Parasitology Laboratory you will perform experiments that support both ongoing and new projects that focus on the development of vaccine against the dog parasite dirofilarial immitis, as well as on the discovery of in vitro and in vivo mechanisms of action for novel parasite-derived immunomodulators and adjuvants on their own and in combination of varied vaccine antigen models.

     

    Responsibilities include:

    • Setting tissue cultures (human and mouse) using defined cells to detect and analyze responses to external stimuli
    • Testing the bioactivities of the recombinant adjuvant using suitable in vitro and in vivo assays
    • Testing the immunogenicity and efficacy of recombining parasite proteins against infection with invective stage larvae
    • Purifying monospecific antibodies for ADCC assays in vitro
    • Immunizing mice and testing the innate and adaptive responses induced
    • Developing protocols, executing them and solving problems as needed
    • Discussing protocols, experiments, outcomes and future plans
    • Making recommendations to improve organizational processes
    • Handling other related tasks as necessary

     

    Qualifications

    To qualify, you must have a Master’s Degree (PhD preferred) in Immunology, Biology, Biochemistry, Molecular Biology, Genetics or a closely related field, along with 5+ years of broad knowledge and experience in innate and adaptive immunology (human and mouse) and vaccinology, with an interest in the translational aspects of these disciplines. Some experience in molecular techniques will also be expected, as will knowledge of general immunological techniques, including particular tissue culture, ELISA, cytokine assays, FACS analysis, handling of mice (including immunization, bleeding and removing organs), vaccinology, and some aspects of molecular biology. This position also requires the ability to interpret experimental results, effectively identify/resolve issues, design new experiments based on previous results, and create new protocols. Superior analytical, oral/written communication and organizational skills are a must.

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